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The Evaluation of the Effect of Tolerogenic Probiotics on the Maturation of Healthy Dendritic Cells versus Immature Dendritic Cells
Conclusion: Our findings revealed that tolerogenic probiotics could induce regulatory DCs by reducing co-stimulatory molecules along with increasing the expression of IDO and IL10 during the differentiation process. Therefore, the induced regulatory DCs probably can be used in the treatment of various inflammatory diseases.PMID:36932870 | DOI:10.22034/iji.2023.91783.2131
Source: Cancer Control - March 18, 2023 Category: Cancer & Oncology Authors: Maryam Rastin Mahmoud Mahmoudi Nafiseh Tabasi Nadia Kia Jafar Hajavi Seyed-Alireza Esmaeili Source Type: research

Rapid, sensitive, and specific detection of SARS-CoV-2 in nasopharyngeal swab samples of suspected patients using a novel one-step loop-mediated isothermal amplification (one-step LAMP) technique
CONCLUSIONS: The results showed that the One-Step LAMP assay is an efficient consistent technique for detecting SARS-CoV-2 among suspected individuals due to its simplicity, speed, low cost, sensitivity, and specificity. Therefore, it has great potential as a useful diagnostic tool for disease epidemic control, timely treatment, and public health protection, especially in poor and underdeveloped countries.PMID:36882699 | DOI:10.1186/s12866-023-02806-z
Source: Cancer Control - March 7, 2023 Category: Cancer & Oncology Authors: Sayyad Khanizadeh Asra Malekshahi Hooman Hanifehpour Mehdi Birjandi Shirzad Fallahi Source Type: research

SARS-CoV-2 antibody response after BBIBP-CorV (Sinopharm) vaccination in cancer patients: A case-control study
CONCLUSION: Full vaccination of COVID-19 by BBIBP-CorV in immunocompromised patients such as cancer patients is safe and effective and could induce antibody response but in lower levels compared to healthy people. Probable causes to have minor antibody response found in males, older ages, individuals with BMI ≥ 25, those without past history of COVID-19 and with hematologic cancers. No significant side effects after vaccination were seen.PMID:36743671 | PMC:PMC9893850 | DOI:10.3389/fmed.2022.1095194
Source: Cancer Control - February 6, 2023 Category: Cancer & Oncology Authors: Fahimeh Safarnezhad Tameshkel Shabnam Abedin Dargoush Bahareh Amirkalali Saeedeh Javadi Ali Ghiaseddin Yousef Alimohamadi Ali Basi Mahin Jamshidi Makiani Farhad Zamani Mohammad Hadi Karbalaie Niya Source Type: research

In vitro and in vivo Evidence on Intra-tumor Injection of Allogeneic Serum for Immunotherapy in a Mouse Model of Colon Cancer
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):549-560. doi: 10.18502/ijaai.v21i5.11042.ABSTRACTIt is believed that preformed antibodies are responsible for blood transfusion reactions and transplant rejections. In order to remove a tumor, the tissue must be rejected. On the basis of transfusion reaction and transplantation immunology, we hypothesized that allogeneic serum can inhibit tumor growth when injected intra-tumor. Initially, an in vitro cytotoxicity test was conducted using the C57BL/6 serum (intact or decomplemented) in combination with the BALB/c-originating CT26 cell line. The CT26 cell line was used to esta...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Erfan Basirat Danial Dehghan Ardeshir Abbasi Nafiseh Pakravan Source Type: research

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